New research suggests that hydroxytyrosol, a compound found
in olives, may protect against metabolic syndrome.
A number of studies have
found that adherence to a Mediterranean-style diet is associated with reduced
incidence of metabolic syndrome, a grouping of risk factors (high blood
pressure, low HDL cholesterol, high triglycerides, high blood sugar and central
obesity) that greatly increase the likelihood of developing cardiovascular
disease or type II diabetes. The benefits of the diet have primarily been
attributed to its low saturated fat and cholesterol content, high fiber and
flavonoid content, and the oleic acid found in olive oil.
Now new animal
research suggests that another olive constituent, hydroxytyrosol, may play a
significant role in the health benefits of the Mediterranean diet as well.
In a study conducted on mice fed a high-fat diet, researchers found that
supplementation with hydroxytyrosol for 17 weeks resulted in reductions in
obesity, hyperglycemia, hyperlipidemia and insulin resistance. They also found
that hydroxytyrosol decreased oxidation levels of lipids and proteins in both
liver and muscle tissues.
The study authors concluded that hydroxytyrosol could
play a role in diabetes and metabolic disease, “suggesting a potential
pharmaceutical or clinical use of hydroxytyrosol in metabolic syndrome
treatment.”
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